What are the different types of injections?



A Hyaluronic Acid injection (HA) helps  lubricate the knee to treat painful cartilage conditions. It involves the injection of hyaluronic acid into the knee over the period of several sessions. Injections are administered in our office once a week, for three weeks.

You will typically start to experience effects of the injections within 1-2 weeks after the final injection. The effects of the treatment can last 6 months. After six months have passed, you can repeat the treatment.

Hyaluronic acid is: An injectable synthetic version of the fluid that naturally exists in your knee.

Common brands of Hyaluronic Acid injections include:

  • Euflexxa
  • Supartz
  • Orthovis
  • Synvisc
  • Hyalgan 

Injection Treatment

Obtaining HA injections can be a difficult process, and it often takes approximately a month to receive them. Many times these injections require extra effort to be covered by insurance companies.

To improve your experience, please review the following guidelines:

Office Responsibilities

  1. Write prescription for the medication
  2. Submit prescription to medication portal
  3. Prior authorization from insurance

Your Responsibilities

  1. Contact the specialty pharmacy regarding the status of your medication
  • If you are notified that the medication requires pre-certification, please contact the us. We are responsible for pre-certification
  • Continue to check in with the specialty pharmacy regarding the status of your medication
  1. Give consent to the specialty pharmacy for the shipping of your medication.

Ship to:

Hospital for Special Surgery
East River Building, 6th Floor, Room 619
Office of Dr. Beth Shubin Stein
523 East 72nd Street
New York, NY 10021

Office Responsibilities

  1. We will contact the patient when injections arrive to schedule appointments.


A Platelet Rich Plasma (PRP) injection serves to support and speed up the healing process for soft tissue conditions. It involves first creating PRP from your blood using a centrifuge to spin your blood sample at high speeds and separate the platelets. These platelets are then injected into the inflamed or injured tissue to aide in a quick recovery.

Platelet Rich Plasma is: A concentrated plasma mixture of platelets(a small cell fragment) that serve to stimulate the healing and clotting process.

Chronic conditions that can benefit from PRP Injections include:

  • Arthritis
  • Chronic tendon injuries
  • Acute ligament injuries
  • Acute muscle injuries
  • Post-operatively to reduce healing time

Injection Treatment

There are 3 steps to your PRP injection, they are:

  1. Your injection treatment starts with the creation of PRP from your own blood.  A blood sample is obtained in the office on the same day as the procedure.
  2. Next,  a centrifuge is used to separate the platelets from the rest of the cells in your blood sample, resulting in a platelet rich plasma.
  3. PRP is then injected to the inflamed or injured tissue using ultrasound guidance to ensure precise placement.

After the injection, it is normal to have increased pain in or around the injection site for  up to several days. It may take days or weeks for you to start to feel the effects of your injections. 

General Precautions

  • Insurances typically do not cover the expense of the procedure
  • Out of pocket expense is $1,000.00 per injection and is paid on the day of the procedure
  • For Meniscal Repair PRP Series Only, 3 injections for reduced rate of $1,500.00
  • Anti-inflammatory medicines should be stopped before and after PRP treatment is given.
  • Avoid exercise after the injection for 3-7 days before beginning a rehabilitation exercise programs

Stem Cell Injections

A Stem Cell is an unspecialized cell that can renew itself through cell division, and under certain physiologic or experimental conditions, can be induced to become tissue, or organ-specific cells. These type of injections represent an innovative regenerative healing treatment that can be used to provide relief to people suffering from a wide range of orthopedic conditions.

 Stem Cell Injections can be used to treat:

  • Arthritis
  • Rotator cuff tears
  • Bursitis
  • Tendinosis
  • Plantar Fasciitis
  • and more

ReNu is a regenerative osteoarthritis (OA) treatment that uses a single injection of nonsteroidal prescription treatment to relieve pain and other symptoms of orthopedic and sports injuries. One injection can provide up to a year’s worth of benefits, and can potentially help you delay or completely avoid surgery. ReNu has helped patients across the country to return to normal daily routines, and return to healthy exercise gradually.

ReNu treatment is typically reserved for patients suffering from pain and discomfort that have experienced minimal to no relief from oral treatments, like NSAIDs (Nonsteroidal Anti-Inflammatory Drug ), or other injections.

ReNu Injections are made of: Amniotic membrane and fluids that are donated after healthy babies are born via C-section. These substances are 100% natural and safe.

ReNu treatment is typically used to treat:

Osteoarthritis in:

  • Knees
  • Hips
  • Ankles
  • Hands/Wrists

Sports injuries, like

  • Partial rotator cuff tear
  • Bursitis
  • Epicondylitis

Orthorpedic injuries, including:

  • Adhesive capsulitis
  • Tendinosis
  • Plantar fasciitis
ReNu Injection Treatment

On the day of your ReNu injection you can expect:

  • A single injection, administered at your doctors office.
  • Your doctor may decide to numb the injection area to prevent minor pain or discomfort.

General Precautions:

For general discomfort, apply ice to the site of the injection for 10 to 15 minutes.

  • Avoid strenuous exercise, heavy lifting, or bending for at least 2 days after your injection.
  • Avoid taking an NSAID for 2 weeks after you injection, as it can affect ReNu’s biologic response.

LIPOGEMS is considered a minimally invasive sterile office procedure, performed with local anesthetic.  LIPOGEMS procedure works to rejuvenate cartilage in the knee by harnessing the innate healing capabilities of adipose (fat) tissue. This process is called a microfat transfer, and it relies on the transformative properties of stem cells present in fat tissue, to grow from one type of cell (fat tissue) into another (cartilage).

It is a 3 step procedure that takes approximately an hour to complete:

  1. Tissue Harvest: The skin is cleaned and the area is numbed, and the adipose tissue is removed from the abdomen.
  2. Processing of Adipose Tissue: This stage consists of several steps (mixing, shaking, transferring, etc.). The During the agitation process, adipose tissue activates into medical signaling cells, which are responsible for stimulating healing and cellular repair.
  3. Injection: Cells from your body, now activated to promote healing, are injected into the knee.

General Precautions:

  • Insurances do not cover the expense of the procedure
  • Out of pocket expense is $3,200 and is paid on the day of the procedure
  • Procedure takes about 1 hour and can be performed in the office
  • Anti-inflammatory medicines should be stopped minimum 10 days before and 6 weeks after LIPOGEMS
  • Avoid exercise after the injection for 3-7 days before beginning a rehabilitation exercise program.
  • Avoid strenuous activity for 3 weeks after the injection
adminTypes Of Injections